Oncologists Wield New Options in Battle with Mesothelioma, Even if Prognosis Looks Grim

Oncologists and other cancer doctors choose what kind of treatment to prescribe with their patient. There are many options. There are no one size fits all treatment course for peritoneal mesothelioma cancer patients. Mesotheliomas lack of agreed-upon treatment is due to low a treatment success rate, rareness, a high mortality rate and a small number of studies providing meaningful stats.

While prospects for patients with mesothelioma have been bleak, doctors have been making progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) Each one of these methods have problems. Mesothelioma patients treated with traditional radiation therapy have not responded well to it. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.

Surgery removes the mesothelial tissue around the tumor. The surgery is difficult and challenging, with unknown effects or benefits to patients. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and different combinations of chemotherapy drugs have been tried without a lot of success. Similar to radiation, focus in research is focusing on treating the physical location of the tumor with emphasis on the pleural cavity.

Many advanced techniques in cancer treatment are tried on mesothelioma patients because of its high fatality rate. These techniques include a biologic therapy called the agent interleukin 2 and anti-angiogenesis drugs like thalidomide. A new drug that has shown results in improving survival is pemetrexed (brand name Alimta).

Considered by oncologists is where the tumor is located, what stage the mesothelioma is in, and the age and health of the patient. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Mesothelioma patients sometimes become involved in clinical trials in this area, and see benefits.

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